The event featured wrestlers and other talent from WWE's SmackDown! brand, a storyline expansion in which WWE assigned its employees. The buildup to these matches and scenarios that took place before, during and after the event were also planned by the script writers. Nine professional wrestling matches were featured on the event's card, which were planned with predetermined outcomes by WWE's script writers.

Like the previous two years, it featured wrestlers exclusively from the SmackDown! brand. The 2005 event was the eighth event under the No Mercy chronology and was held on October 9 at the Toyota Center in Houston, Texas. A second No Mercy was then held later that same year in October, but in the United States, which established No Mercy as the annual October PPV for the promotion. No Mercy was first held by World Wrestling Entertainment (WWE) as a United Kingdom-exclusive pay-per-view (PPV) in May 1999. It remained on the chart for four consecutive weeks. When the event was released on DVD, it reached a peak position of fourth on Billboard's DVD sales chart for recreational sports. The event was claimed to be 'unmerciful' by Canadian Online Explorer's professional wrestling section, as they rated none of the matches higher than a five out of ten. The event received 219,000 pay-per-view buys, which was greater than the 193,000 buys the previous year's event received. Another primary preliminary match was a standard match between John 'Bradshaw' Layfield (JBL) and Rey Mysterio, which JBL won. The Ortons won the match after placing Undertaker inside the casket and closing it. One of the featured preliminary matches was a Casket match between The Ortons ( Randy and 'Cowboy' Bob) and The Undertaker. This would be Guerrero's final pay-per-view match before his sudden death one month later. The main event was a standard wrestling match, in which World Heavyweight Champion Batista defeated challenger Eddie Guerrero to retain his title. Three of the four championships exclusive to the SmackDown! brand were contested for one was lost while the other two were retained. Nine professional wrestling matches were scheduled on the event's card. The event took place on October 9, 2005, at the Toyota Center in Houston, Texas.

It was held exclusively for wrestlers from the promotion's SmackDown! brand division.

The 2005 No Mercy was the eighth No Mercy professional wrestling pay-per-view (PPV) event produced by World Wrestling Entertainment (WWE). Promotional poster featuring Eddie Guerrero

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